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The results of the PIONEER-3 trial have now been published in the renowned journal Journal of the American Medical Association (JAMA) and are said to be trend-setting for future therapy of type 2 diabetes.

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Peak GLP-1 increases were significantly higher (~32%) after RYGB at both follow-ups (p<0.05)

Among regular drinkers, consumption plummeted from 23.2 to 7.8 units per week a 68 percent reduction, which Professor le Roux noted is comparable to that achieved by nalmefene, a drug used to treat alcohol use disorder in Europe. The potential for these weight loss drugs to reduce alcohol consumption could yield additional public health and economic benefits

The cost of medication, not included in the plan, could be upward of $1,000 a month if not covered by insurance.