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also showed that MM-151 is active against all known EGFR ECD mutants and is comparable in efficacy to panitumumab against cetuximab-resistant variants that retain sensitivity to panitumumab, particularly EGFR K467T and S492R (Arena et al., 2016)

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It occurs in HIV/AIDS as a side effect of antiviral treatment

Ranjan A, Ramachandran S, Gupta N, Kaushik I, Wright S, Srivastava S, et al

Frequency of the transthyretin Val30Met mutation in the northern Swedish population
