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Nevertheless, the prognosis of PDAC patients remains suboptimal owing to resistance to GEM chemotherapy [22]

J Pajoohandeh 15:16 Koushik B, Rajen D, Debanjana S, Nimisha P, Asim KB, Mohuya PP, Nandini Sh, Gargi RC, Aniruddha B, Rajkumar M, Krishnendu A, Prity C, Prithviraj K, Alak KS (2022) Polycystic ovary syndrome and its management: in view of oxidative stress

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This state is marked by more pronounced systemic-inflammatory-response features than in canonical and low-grade inflammation, including cytokine elevations by orders of magnitude, coagulopathy with systemic microthrombosis, systemic tissue injury, and activation of the hypothalamicpituitaryadrenal distress axis, and therefore requires integrated criteria for differential diagnosis [926]

73 These findings suggest that this approach leads to more efficient immune suppression