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[DOI] [PMC free article] [PubMed] [Google Scholar] 196.Bejarano L, Jordao MJC & Joyce JA Therapeutic targeting of the tumor microenvironment

doi: 10.1111/1346-8138.12178

Dosage: 1,0002,000 IU/day or based on blood levels

With reference to this physiological time duration of a systemic insulin response, 2-hour treatment of glargine to ex vivo cerebellar tissue cultures was conducted, which further validated the responsiveness to insulin in this brain region (Fig

doi: 10.1016/j.tox.2005.08.006 35 ChmelarRBuchananGNeedEFTilleyWGreenbergNM

Such biomarkers could help identify patients most likely to respond to treatment and could facilitate personalized treatment approaches
