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Saponins 117 have an aromatic configuration with different side chains depending on the type of compound

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Although studies have shown that Nrf2 and Nrf2-activating chemicals have opposing effects on the NLRP3 inflammasome that are not dependent on Nrf2-mediated gene expression, both effects are independent of the transcriptional activity of Nrf2 [129]

However, tryptophan is an essential amino acid

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