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Description
Melanotan 1 has also been investigated as a treatment for patients who have undergone photodynamic therapy with porfimer sodium
Many practitioners recommend starting at a low dose (100-250 mcg) and titrating up to reduce nausea severity
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Certain genetic profilessuch as variants in the GIPR (glucose-dependent insulinotropic polypeptide receptor) locuscorrelate with stronger nausea sensitivity during the initial titration phase

Functional analysis of the lipoglycodepsipeptide antibiotic ramoplanin
However, for most research timelines involving Melanotan 2, this is often an unnecessary complication