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Systematic review with meta-analysis of active herpesvirus infections in patients with COVID-19: Old players on the new field

This article clearly distinguishes between FDA-approved uses (none) and investigational findings

8 , e3009 (2017)

Moreover, as MnO 2 nanoparticles could be decomposed to harmless water-soluble Mn 2+ ions that are rapidly excreted by kidneys, there should be no long-term toxicity concerns for MnO 2 nanostructures when they are used for in vivo applications, unlike many other non-biodegradable inorganic nanomaterials 23, 29

demonstrated that the Nrf2 agonists 4-octyl-itaconate and clinically approved dimethyl fumarate can inhibit the replication of several types of virus, including SARS-CoV-2 68 and ZIKV by an IFN-independent pathway 67

even minor impurities can compromise results