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the pharmacological elevation of serum UA does not result in any reduction in the progression of PD

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Sever et al., 2019) and blood supply

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doi: 10.1038/s41591-024-02931-w 126 FranceschiF.OjettiV.CandelliM.CovinoM.CardoneS.PotenzaA.et al

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Tofacitinib also significantly inhibits IL-22-induced CXCL1 and CXCL5 expression in human colonic tissues, suggesting that targeting the IL-22/CXC chemokine axis through JAK/STAT inhibition may be a viable therapeutic strategy

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