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Sin embargo, la sntesis de novo de colina en los humanos no son suficientes para satisfacer sus necesidades metablicas, de modo que los humanos sanos alimentados con dietas deficientes en colina desarrollan hgado graso, dao heptico, y/o dao muscular (ver Deficiencia)

The term lipotoxicity refers to the consequences of excessive buildup of lipids in the liver, skeletal muscle, pancreas and other non-adipose tissue, causing insulin resistance and failure of the cells (45)

Proton pump inhibitors, H2 receptor antagonists, and prokinetic agents may have altered effectiveness due to tirzepatides effects on gastric function

In addition, L-carnitine has been shown to have anti-aging properties

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