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Other studies also indicate pro-inflammatory mediators induce MUC5AC via NFkB [66]

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Moreover, reduced sirtuin (class III HDAC) activity has been observed in Menieres disease, a disorder frequently accompanied by tinnitus, correlating with increased oxidative stress and neuroinflammation (Scuto et al., 2020)

[DOI] [PMC free article] [PubMed] 4.Klop B, Elte JWF, Cabezas MC
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