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Notably, the MTHFR rs1801133 TT genotype has been associated with higher PASI 90 response rates, indicating better therapeutic outcomes, while the CT + TT genotypes correlate with an increased risk of liver function abnormalities in patients with psoriatic arthritis (Zhu et al

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doi: 10.2147/IJN.S169399

Hyaluronic acid (HA), a negatively charged linear glycosaminoglycan composed of D-glucuronic acid and N-acetyl-D-glucosamine, has been shown to enhance drug accumulation in cancer cells that overexpress CD44a non-kinase transmembrane glycoproteinwhen used to modify chitosan nanoparticles (Wang et al., 2017