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In an in vitro study on human placental membrane vesicles, very high concentrations (approximately 100 times higher than the highest reported levels in blood), inhibited L-alanine transport (Asai et al., 1985)
doi: 10.1210/clinem/dgad212 166 KotsifakiAMaroulakiSKaralexisEStathakiMArmakolasA

(162) Song, M

(2021) human knee study used intra-articular injection (directly into the joint space), which requires clinical supervision

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10.1038/nature21407 186