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Catecholamines, including dopamine, norepinephrine, and epinephrine, play a significant role in regulating renal hemodynamics, renal tubular transport, and blood pressure

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These alterations also control the pattern of expression in various genes during spermatogenesis and fertilization under regular biological conditions [114]

Dedicated safety-pharmacology studies covering cardiovascular (including hERG/QT), respiratory, and central-nervous-system function