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PMCID: PMC10376088

Induction of Gpx4-deficient macrophages with IL-4, which triggers M2 macrophage activation, severely disrupted the cellular redox balance and led to ferroptosis

doi: 10.1007/BF03345194

A.RocaM.KohlsE.PenninxB.WatkinsE.et al

In one notable double-blind RCT published in the Journal of Clinical and Experimental Hepatology , 60 patients with NAFLD received either 600 mg of NAC twice daily or placebo for three months
It is also common to see higher levels of taurine excretion during gut infections, which may cause taurine deficiencies