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This is the foundational reason for the 20mg/ml concentration see the standard 20mg/ml product page for the full dosing precision rationale

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Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy