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10.1016/j.matbio.2014.08.014 113 JungerS.Gantenbein-RitterB.LezuoP.AliniM.FergusonS

Side effects like reactions at the injection site are common

This observation revealed that urocortin does not reduce renal damage caused by bilateral renal ischemia [ 95 ]

It is administered intravenously, and may lead to adverse effects such as bradycardia, tachycardia, hypertension, peripheral oedema, and rash [32]

The condition is mostly genetic, but several factors can make it worse: Dry skin Cold or dry weather Hormonal shifts (such as during puberty or pregnancy) Skin conditions like eczema KP tends to be more noticeable when your skin lacks moisture or is exposed to irritants
