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M.AvantsB

The enzymatic reaction was initiated by adding 1 mL of GPx enzyme solution (3000 units/liter) to 9 mL of a mixture containing potential interfering substances

Anthony RM, MacLeay JM, Jewell DE, Brejda JJ, Gross KL

This indicates that iron overload is detrimental to glutathione-stransferase activity due to its ability to induce oxidative stress in the cells

In the absence of glutathione, it is likely that coenzyme A maintains redox homeostasis in the bacterium, as it is the most abundant LMW thiol in L

Mechanistically, the neuroprotective effect is mediated by the PI-3K activation (Hossain et al., 2002)
