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Gout, the most common inflammatory arthritis worldwide, arises from the deposition of monosodium urate (MSU) crystals in joints and soft tissues, driven by chronic hyperuricemia (Nakayama et al., 2023)

2012 doi: 10.1056/NEJMoa1211721

Bertolotti, A

By contrast, we know that G6PD-null mutations are lethal to the mouse embryo

We carefully examined the literature but were unable to find any studies that assessed the therapeutic potential of CGRP antagonists/blockers in preclinical or clinical COPD studies

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