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Diabetes group recommends against compounded GLP-1s

Metformin, though not a GLP-1 agonist, shares the property of reducing stomach acid and interfering with b12 absorption
When B12 is low, people might feel tired, weak, confused, or irritable

Education into practice Practice How often do you evaluate B 12 deficiency related symptoms in individuals at high risk of developing this, such as vegetarians and vegans, or people with increased risk of B 12 malabsorption, such as individuals with type 1 diabetes or Hashimoto hypothyroidism

Depending on how long you've had the deficiency and how much damage it's done, it could take at least 4 months before your symptoms improve
