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doi: 10.3390/ijms22041623 20 BarretoE

For each field, integrated optical density (IOD) was calculated using Image-J software

1 Introduction RNA-LNP therapeutics is an advancing field with substantial potential for disease prevention or treatment (Hou et al., 2021
Petersel, D
M2b phenotype activation induced by immune complexes and TLRs agonists increases the expression of IL-1, CD86, suppressor of cytokine signaling 3 (SOCS3), IL-6, IL-10, involved in phagocytosis and removal of damaged tissue debris (Franco and Fernndez-Surez, 2015

NAD + metabolic disturbance NAD + has neuroprotective effects in acute axonal injury, chronic nerve stress, and different neurodegenerative diseases associated with excitotoxicity [116]
