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Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

PMID: 32941710

4A), and the results revealed an upregulation of IRE1 (an ER stress marker), indicating ER stress activation, reduced p62 levels, and increased LC3BII levels within 012 h of PFOS treatment

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A., Cooper, M., Sargeant, A

Metabolic changes at the micro level (cellular functions, membranes, mitochondria) lead to macro alterations that impact the body as a whole and eventually manifest as age-related chronic and degenerative diseases