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With central neural blockade these changes may be attributable to block of autonomic fibers, a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system

The follow-up that matters for this specific compound landed in 2018, when a small-molecule NNMT inhibitor was given to obese mice

Investigation of the peptide AOD9604 in an ovine osteochondral defect model

For continuous lumbar or caudal epidural anesthesia for non-obstetrical procedures, higher doses need to be administered to achieve adequate anesthesia

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