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Out of all the studies done in animals and the few human clinical trials that exist, no adverse side effects or toxicity events have been reported
This can lead to digestive upset or skin irritation as the body tries to process the unabsorbed material
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Opheim et al., 2021
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial
