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Long-term metformin treatment is associated with reduced serum B12 in a dose- and duration-dependent manner

Existing reviews have further highlighted that pharmacokinetic and safety characterization in humans remains incomplete, complicating clinical counseling regarding timing of discontinuation, perioperative risk stratification, and postoperative resumption (Rahman et al

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Importantly, EPO prevents Fas/FasL-mediated apoptosis in erythroblasts [109] and CFU-e cells [31]