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Retatrutide is a triple receptor agonist (GLP-1, GIP, and glucagon) that suppresses appetite, improves insulin sensitivity, and promotes overall weight loss averaging 24.2% over 48 weeks in clinical trials

doi:10.1007/s00228-019-02666-5

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PPAR-gamma is a major driver of the accumulation and phenotype of adipose tissue Treg cells

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