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Instead, it may be that chronic diseases cause low glutathione levels, which then can exacerbate the conditions due to an inability to counteract the increasing levels of oxidative stress

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Leffler DA, Kelly CP, Green PHR, Fedorak RN, DiMarino A, Perrow W, Rasmussen H, Wang C, Bercik P, Bachir NM, Murray JA

Moreover, smooth-fitting curve analysis identified a threshold effect: below 358.7 pg/mL, each 10 pg/mL increase in vitamin B12 was associated with a 4.4% increase in clinical pregnancy rate (OR = 1.04, P = 0.03), beyond which no further benefit was observed

The expression of FOXO4 in the cytoplasm of keloid fibroblasts was significantly lower than that in normal skin fibroblasts ( p = 0.03