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Always speak with your physician.

Gastric acid and pepsin in the stomach release B12 from these dietary proteins, allowing it to bind with R-proteins (haptocorrins) secreted in saliva

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While parenteral B-12 therapy is generally safe, specific populations and medical conditions carry elevated risk

89 In contrast, some recent studies have found vitamin D status to have been unaffected by metformin use 62 and a placebo-controlled study found no effects of the drug at 4 or 16 months use in people with T2DM