does glp-1 make you lose weight Agonists: Using Semaglutide, Tirzepatide, and Orforglipron for Loss and Obesity Unlocking Sustainable Weight Loss with

and liraglutide, 30 g/kg per day, ip, twice daily)

doi: 10.1161/CIRCULATIONAHA.124.071689

Simplistically, GLP-1s like Ozempic or Mounjaro are appetite suppressants

The study also found that less than half of the UK audience are aware that GLP-1s are prescription-only medicines

To put this in perspective, the FDA approval of Ozempic was based on evidence from seven clinical trials with over 4,000 participants in 33 different countries

Nature DOI:10.1038/s41586-026-10444-4 Abstract A brain reward circuit inhibited by next-generation weight-loss drugs in mice Glucagon-like peptide 1 receptor agonists (GLP1RAs) effectively reduce body weight and improve metabolic outcomes