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Neuroprotective effects of coenzyme Q10-loaded exosomes obtained from adipose-derived stem cells in a rat model of Alzheimers disease

Notably, further studies discovered an inducible GPX4 transcript-variant (iGPX4) in NAFLD conditions, and suppression of iGPX4 by siRNA-iGPX4 significantly alleviated oxidative stress and cellular damage by impairing ferroptosis

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Patients often describe it as inducing discomfort more severe than the compression syndrome itself

However, bilirubin is also neurotoxic at such high concentrations through mechanisms involving lipid peroxidation, as is for the case of hemin [233]