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Description
Bone marrow characterization in COPD: A multi-level network analysis

In addition, iron storage in ferritin requires formation of the glutathione-iron complex, which is delivered to ferritin via the chaperone poly(rC) binding protein 1 (PCBP1) (Patel et al., 2021)
1g, h), and influenced by the biomarkers of antioxidative activity

Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults

The first axis involves direct, irreversible damage to core cellular components, causing clustered oxidative DNA lesions and reactive aldehydes, leading to a progressive disruption of metabolic homeostasis and the accumulation of dysfunctional cellular machinery [234, 235]

used the rat pancreatic beta cell line Rin-5F to induce cell death via DM mimics, including high glucose, H 2 O 2 , and STZ, and reported that these factors accumulate ROS and iron, inactivate NRF2, and reduce the mitochondrial membrane potential, while treatment with Fer-1 mitigated these effects [87]