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Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 4.0, DCTD, NCI, NIH, DHHS

Creatinine levels typically rise when: the kidneys cannot filter it efficiently due to reduced glomerular filtration rate (GFR), dehydration temporarily reduces renal blood flow, creatine supplements increase creatine turnover, intense exercise or large muscle mass increases baseline production, or certain medications (like NSAIDs or contrast dye) reduce kidney blood flow

Seiwerth, S., Milavi?, M., Vukojevi?, J., Gojkovi?, S., Krezi?, I., Batelja Vuleti?, L., Horvat Pavlov, K., Petrovi?, A., Sikiric, S., Vrane, H., Prtoric, A., iek, H., ?urain, T., Dobri?, I., Stareini?, M., trbe, S., Kneevi?, M., ola, M., Kokot, A., & Sever, M

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Circulation 123:e18e209

In 1979, the Chinese Keshan Disease Research Group proved that selenium deficiency is a necessary condition for Keshan disease