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However, compared with humans, the ratio of the oral dose to the serum concentration seems to be higher in rats than in humans, making it difficult to directly apply relevant studies to humans (Meftah et al., 2021)

Esterified or DHA-bound AST appears to enhance bioavailability and efficacy compared with unmodified AST

Avoid alcohol, excessive caffeine, smoking, and certain medications like high-dose paracetamol, chemotherapy drugs, and specific antibiotics

Ryoo K, Huh SH, Lee YH, Yoon KW, Cho SG, Choi EJ

There are no effective treatments for CRC in clinical practice, and CRC patients tend to develop problems such as cancer recurrence in their prognosis

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