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The importance of intracellular targeting of cortactin has been shown with a cell-permeable peptide that binds cortactin, and inhibits the invasion of a range of cancers including glioblastomas (Hashimoto et al., 2006)

Recent research discovered that a high-activity PobA variant, Y385F/T294A-PobA, was developed from the hydroxyphenylacetic acid hydroxylase of Pseudomonas aeruginosa

10.1007/s10637-019-00766-768[Epub ahead of print] Invest

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501,502 Key recommendations: T1DM patients: Early and intensive glycemic control is recommended to prevent or delay the onset and progression of DPN and DAN