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Archived from the original on April 30, 2021

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Huber C, Wachtershauser G

doi: 10.1186/s13075-024-03308-7 51 VarsanyiCBirgeRB

Prior to conducting PCA and OPLS-DA analyses, all quantitative data were subjected to normalization using isotopically labeled internal standards followed by Pareto scaling preprocessing (where each variable is divided by the square root of its standard deviation), aiming to reduce the impact of concentration heterogeneity while preserving the data structure

For example, might people with borderline deficiency show modest metabolic responses that current trials missed

This results in water expulsion and network contraction, leading to gel formation