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But now it's exactly the reverse." Another possible target for modulating microglial activity is the complement system, a signaling pathway that can tag molecular danger signalsor mistakenly, synapsesfor microglia to consume

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Up to 40 studies covering almost 1,500 human subjects have been reported since the 1920s in the literature using intravenous infusions of bilirubin with a relatively good safety profile (for a review of these studies, see [134])

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