tirzepatide makes me gassy bloating from Tirzepatide vs. Gastroparesis Side Effects: What to Know How Tirzepatide Helps Lose Weight

According to Eli Lilly, the manufacturer of Zepbound, tirzepatide must be stored as follows: Unopened Zepbound pens must be refrigerated between 36F and 46F (2C8C) until first use

In clinical trials for tirzepatide, the most common side effects involved mild to moderate gastrointestinal problems

In the SURMOUNT trials for obesity, gastrointestinal adverse events increased with dose: 39% at 5 mg, 46% at 10 mg, and 49% at the 15 mg dose

Pull 0.1 mL (10 units), and you get one-tenth of those 5 milligrams

Additionally, if the pen has been frozen (even if subsequently thawed), it must be discarded regardless of appearance

Take with food to maximize absorption and minimize fishy aftertaste