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CCR2/CCR5-mediated macrophage-smooth muscle cell crosstalk in pulmonary hypertension

As demonstrated by Arts et al
We have earlier discussed in detail the role of the insulin/IGF-1-driven AKT/IKK/NF-B signaling pathway in the aging process [77]

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AGEs accumulate continuously on long-lived vessel wall proteins with aging and at an accelerated rate in diabetes
