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Butyrate metabolism diverges between normal intestinal epithelium and cancer cells: Normal epithelia utilize butyrate via -oxidation, whereas CRC cells exhibit diminished catabolic capacity due to the Warburg effect, leading to intracellular accumulation (155)

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Subjects were divided by LH level similar to the first study, this time with 16 patients in the low LH group and 8 in the higher LH group

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The skin gradually regains its density and elasticity