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Activated RagA/B binds GTP, and RagC/D binds GDP and is anchored to the lysosome by the Ragulator protein (Wolfson et al., 2016

The increased epithelial thickness seen in the I/R group is attributed to interstitial edema and inflammatory infiltration, which are prevalent during testicular torsion-detorsion 45

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with a meta-analysis suggesting anticonvulsants, which generally modulate glutamatergic, GABAergic and possibly other excitatory or inhibitory neuronal activity, have modest but significant efficacy in the treatment of alcohol dependence (Pani et al., 2014)

K562 cells were cultured in RPMI 1640 (Gibco, 11875119) supplemented with 10% (v/v) fetal bovine serum (FBS) (Takara Bio, 631367) and passaged 1:4 every 3 d to maintain a maximal cell density of 800,000 cells per ml