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Kinetic parameters of 5-reductase activity in stroma and epithelium of normal, hyperplastic, and carcinomatous human prostates

Activin A signals by binding to one of the two types II receptors on the cell surface (ActRIIA or ActRIIB), which leads to the enrolment of type I receptors ActRIB (ALK4), and to the activation of Smad-dependent or Smad-independent signalling pathways [18]

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The pH-dependent toxicity of ionizable organic compounds in organisms conforms to a toxicokinetic ion-trapping model 3,13