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Further studies showed that CDC appears to be a more prominent effector mechanism for daratumumab [22, 28], with evidence suggesting that isatuximab induces CDC only in the presence of high CD38 receptor density [24, 32]

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94,95 All of the studies had small sample sizes, and study details are mostly not well reported

The practice of adding a small DMSO volume before aqueous solvent is also worth internalizing as a first-line technique for any peptide you have not previously worked with, rather than a last resort