nadph-dependent glutathione reductase mechanism and -independent disulfide systems Thioredoxin Glutathione Reductase from Schistosoma
Description
These complexes are biologically inactive, and no harm from them has been detected
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10.1080/1744666X.2016.1195686 162 OmoriK.OhiraT.UchidaY.AyilavarapuS.BatistaE

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They showed that doses above 400 mg/kg caused an almost complete exhaustion of GSH levels in the liver and a sharp rise in the amount of covalent binding (Figure6B)

The treatment is regarded as relatively safe, but like any medicine, has potential side effects: Diarrhoea Dizziness Headache Hot flush Nausea Skin reactions Urine discolouration If you are allergic to cobalt please notify your clinician (1-3% of the population have this allergy)
