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(2016) 14:160211.e5

[Google Scholar] [PubMed] [CrossRef] 105

The alternative pathway for LTA 4 metabolism is prominent in cells expressing the enzyme LTC 4 synthase (LTC4S or glutathione- S -transferase), which is found on the nuclear envelope of cells and adds the tripeptide glutathione (glutamyl-cysteinyl glycine) to carbon-6 to yield peptido-leukotriene C 4 (LTC 4 , 5 S ,6 R - S -glutathionyl-7,9,11,14-( E,E,Z,Z )-eicosatetraenoic acid), the first of the 'cysteinyl leukotrienes'

doi: 10.5943/cream/11/1/34

doi: 10.1177/1362361307089518