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As with any therapeutic intervention, individualized assessment, clear patient communication, and systematic monitoring remain essential

The deletion of Bhmt gene in mice resulted in an appreciable reduction in SAM/SAH ratio (i.e., the methylation potential) and a several-fold increase in hepatic and plasma total homocysteine (tHcy) concentrations (Teng et al., 2011)

Martinotti, G., Reina, D., Di, Nicola M., Andreoli, S., Tedeschi, D., Ortolani, I., Pozzi, G., Iannoni, E., D'Iddio, S., and Janiri, L

The impact of thyroid hormones on patients with hepatocellular carcinoma

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Per alcuni sarebbe necessario un apporto esterno della sostanza, atto a bilanciare il fabbisogno metabolico