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1A), indicating that these two DUBs, Ubp2 and Ubp3, play a role in editing the polyubiquitin chain on uS10

Disturbed genomic integrity induces oxidative genetic damage, DNA oxidation, the activation of proto-oncogenes, and the inactivation tumour suppressor genes leading to proliferative effects and mutagenesis (113, 114)

10.1016/j.jamda.2013.03.022 178

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10.1016/j.ebiom.2019.11.026 32 BirsaN.BenthamM

It's also why we went the harder route on our formula
