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5-amino-1-methylquinolinium) combined with low-fat diet (LD) promoted dramatic whole-body adiposity and weight loss in diet-induced obese (DIO) mice, rapidly normalizing these measures to age-matched lean animals, while LD switch alone was unable to restore these measures to age-matched controls in the same time frame

In several robust trials, a marked decrease in the incidence of acute respiratory disease, ischemic heart disease, hypertension disease, pulmonary fibrosis, coronary artery disease, diabetes mellitus, Alzeimers disease, deforming osteoarthrosis, and osteoporosis was observed as compared to control animals 6

It has been shown to promote sleep in several species, including rabbits, rats, mice, and humans, with varying effects on REM sleep in cats 1

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Zitzmann, M., & Nieschlag, E

Reichert, C