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Their recently discovered enrichment in two additional layers within focal adhesions and their role in regulating myosin IB and IC affinity to actin suggest they modulate the precise dynamics of adhesion formation and turnover that is needed for persistent migration

Brazilian J Med Biol Res = Rev Bras Pesqui medicas e Biol

( 45 ) 135 135 /, 726 ./

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Pharmacokinetics and pharmacodynamics of the cytolytic anti-CD38 human monoclonal antibody TAK-079 in monkey - model assisted preparation for the first in human trial