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Based on evidence reviewed in Cristofori et al, SCFAs like butyrate enhance TGF-/Smad3 signaling in B cells, promoting IgA class switching while suppressing IgE production through HDAC inhibition and GATA3 downregulation (129)

NCRCCHD-2021-KP-02), the Beijing Key Laboratory of Molecular Diagnosis and Study on Pediatric Genetic Diseases (No

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At this time, additional randomized placebocontrolled studies are clearly required to determine therapeutic efficacy for cardiovascular diseases

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However, bruising is typically minor and resolves with time