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Am J Physiol Endocrinol Metab 278:E405412 Lyons J, Rauh-Pfeiffer A, Yu YM, Lu XM, Zurakowski D, Tompkins RG, Ajami AM, Young VR, Castillo L (2000) Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet

That is, the main function attributed to the tight junction proteins is the gate and fence function, which allows the paracellular transport of some solutes and molecules but prevents the intramembrane transport of proteins, lipids, and microbial-derived peptides 25,26

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Dufour DR, Lott JA, Nolte FS, Gretch DR, Koff RS, Seeff LB