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14,105 Remarkably, ZnT10 demonstrates the molecular features of a manganese transporter, likely attributed to its possession of an Asn residue rather than His in the TM helix II

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First, 3PG is oxidized to 3-phosphohydroxypyruvic acid (3PHP) by phosphoglycerate dehydrogenase (PHGDH), reducing NAD+ to NADH

However, targets for drugs that are essential for tumor cell survival or immune evasion and can be tailored to patients tumor characteristics remain to be identified [54]

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